


As the second leading cause of cancer death in the US, understanding your risk of colorectal cancer is vital. This tool is designed for anyone not yet diagnosed with colorectal cancer.
Simply answer a few questions and upload your DNA report (from companies like AncestryDNA or 23andMe). Don't have a DNA file? We can calculate your risk using lifestyle factors alone.
Your privacy is protected! We never store your answers or genetic data.
This tool is for educational purposes only and does not replace medical advice or diagnosis from a health care provider. Read full Disclaimer and Terms of Service
The human genome is like a set of instructions that tells your body how to work. It contains millions of tiny differences called genetic variants, which can affect your health in different ways. For a complex disease like colorectal cancer, most people don’t have just one gene that increases risk—instead, many genes each play a small role. When these effects add up, it is called polygenic risk.
Your genes, together with your lifestyle—things like diet, exercise, and smoking—can increase or decrease your risk for developing colorectal cancer.
Our tool calculates a Polygenic Risk Score (PRS) that adds together the effects of many genetic variants linked to colorectal cancer, along with your lifestyle habits.
Upload your DNA report from AncestryDNA, MyHeritage DNA, 23andMe or another services. If you don’t have this report, don’t worry. We can use your lifestyle information only.
Answer questions about your lifestyle, like diet, exercise, and smoking habits.
After you upload your DNA report and answer lifestyle questions, you will immediately get a printable report that explains your risk of colorectal cancer. Based on your personal risk it will provide recommendations for colorectal cancer screening (when to start screening, and how often) and tell you about lifestyle changes that may help lower your risk. Screening tests check for a condition, like cancer, in people who don’t have any symptoms. Your doctor or health care provider can tell you more about how making certain changes might affect your overall health and other risks.
Follow the recommendations in your report, which include sharing the report with your health care provider. Together, you can create a plan to reduce your risk.
Your risk can change over time, as your health history or lifestyle changes. Because of this, we encourage you to use this tool every 3-5 years. That way you’ll always be aware of your risk and can take steps to lower it.